Abstract

Research Article

The influence of opioid on the microstructural organization of the Wall OT the uterus of the white laboratory rat

Mateshuk-Vatseba LR, Ivankiv Ya T and Ivankiv TM*

Published: 11 December, 2019 | Volume 2 - Issue 2 | Pages: 135-137

Drug addiction is one of the burning problems in the modern society. Annually there is a steady increase in the level of drug abuse. United Nations Office on Drugs and Crime publishes “World Drugs Report 2018”, where it was reported that about 275 million people (almost 5.6% of the world population) aged 15-64 used drugs at least once in their lives, and opium production increased by 65% in 2016-2017 [1-3]. Therefore, the question of studying the influence of drugs on the structural organization of organs remains open and relevant [4,5].

Read Full Article HTML DOI: 10.29328/journal.cjog.1001036 Cite this Article Read Full Article PDF

References

  1. Organization WH. Guidelines for the psychosocially assisted pharmacological treatment of opioid dependence. New York: World Health Organization; 2009. PubMed: https://www.ncbi.nlm.nih.gov/books/NBK143185/
  2. O’Connor G, McMahon G. Complications of heroin abuse. Eur J Emerg Med. 2008; 15: 104-106. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/18446076
  3. World Drug Report 2018. (United Nations publication, Sales No.E.18.XI.9) [Internet]. 2018. https://www.unodc.org/wdr2018.
  4. Center for Behavioral Health Statistics and Quality.(2015). Behavioral health trends in the United States: Results from the 2014 National Survey on Drug Use and Health (HHS Publication No. SMA 15-4927, NSDUH Series H-50). http://www.samhsa.gov/data/
  5. Kolodny A, Courtwright DT, Hwang CS, Kreiner P, Eadie JL, et al. The prescription opioid and heroin crisis: a public health approach to an epidemic of addiction. Annu. Rev. Public Health 2015, 36: 559-574. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/25581144
  6. Alimbetova AR. The study of the structure of gynecological diseases in the modern aspect. Bulletin of the Kazakh National Medical University. 2016; 1: 584-7.
  7. Ivankiv Ya T. Morphological features of human and white laboratory rat uterus. International scientific and practical conference. Prospects for the development of medicine in EU countries and Ukraine. Wloclawek, Republic of Poland. 2018: 21-22.
  8. Benningfield MM, Dietrich MS, Jones HE, Kaltenbach K, Heil SH, et al. Opioid dependence during pregnancy: relationships of anxiety and depression symptoms to treatment outcomes. Addiction. 2012; 107: 74-82. PubMed: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315620/
  9. Kayacan N, Ertugrul F, Arici G, Kkar M, Erman M. in vitro effect of opioids on pregnant uterine muscle. Adv Ther. 2007; 24: 368-375. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/17565928
  10. Gartry CC, Oviedo-Joekes E, Laliberté N, Schechter MT. The trials and tribulations of implementing a heroin assisted treatment study in North America. Harm Reduction J. 2009; 6: 2. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/19159475
  11. Onysko RM, Paltov YV, Fіk VB, Vіlkhova ІV, Kryvko Yu, et al. Method simulation of physical opioid dependence in rats. Ukrainian patent № 76564. 2013.
  12. Yoo KY, Lee J, Kim HS, Jeong SW. The effects of opioids on isolated human pregnant uterine muscles. Anesth Analg. 2001; 92: 1006-1009. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/11273940
  13. Dehghan M, Jafarpour M, Mahmoudian A. The effect of morphine administration on structure and ultrastructure of uterus in pregnant mice. Iranian J Reprod Med. 2010; 8: 111-118.
  14. Tang X, Chen Y, Ran H, Jiang Y, He B, et al. Systemic Morphine Treatment Derails Normal Uterine Receptivity, Leading to Embryo Implantation Failure in Mice1. Bio Reprod. 2015; 92. PubMed: https://www.ncbi.nlm.nih.gov/pubmed/25855262

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