Figure 1

Addition of dydrogesterone to vaginal progesterone and transfer postponement improve outcomes in patients with low progesterone levels in hormonally substituted cycles for frozen-thawed embryo transfer

Anne Lecourt, Julie Labrosse, Maeliss Peigné, Claire Vinolas, Laetitia Laup, Christophe Sifer, Michael Grynberg and Isabelle Cedrin-Durnerin*

Published: 11 March, 2022 | Volume 5 - Issue 1 | Pages: 027-035

cjog-aid1103-g001

Figure 1:

Endometrial preparation. Provames® is started on the first day of a natural menstrual cycle, after 10 days of treatment, a monitoring by blood sample to measure estradiol (E2), progesterone (P) and LH levels and by vaginal ultrasound is performed. If endometrial thickness was ≥ 7 mm with a triple-line pattern and serum P levels were lower than 1.5 ng/mL, Progestan® was initiated in the evening (day-0 of P administration D0) and estrogen administration was switched from the vaginal to the transdermal route (Vivelledot®). Serum P was measured in the morning on the day following exogenous P introduction after the second vaginal administration (day-1 of P administration, D1). When P levels were ≥11 ng/mL, FET was performed on day 2 (D2) of progesterone administration for day-2 embryos, on day 3 (D3) for day-3 embryos and on day 5 (D5) for blastocysts (group VMP in phase T. When P levels were < 11 ng/mL, Duphaston® was added to vaginal P and FET was postponed by one day (group DYD+VMP 1 day postponed T).

Read Full Article HTML DOI: 10.29328/journal.cjog.1001103 Cite this Article Read Full Article PDF

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