Early Online (Volume - 8 | Issue - 4)

Peripartum Cardiomyopathy: Early Diagnosis and Management in Secondary Care Hospital

Published on: 29th October, 2025

Background: We report a case of Peri-Partum Cardiomyopathy in a 28-year-old Primigravida, who came in labor and underwent a Caesarean Section in view of meconium-stained liquor, fetal distress. On day 4 post-partum, she complained of a sudden onset of shortness of breath, cough, and restlessness in the morning. The patient had no prior history of heart disease or respiratory disease. Patient developed sudden onset tachypnoea and tachycardia with bilateral crepitus. On further evaluation, she was diagnosed with Peripartum Cardiomyopathy. Results: The case was successfully managed by a multi-disciplinary team using dobutamine, diuretics, and Angiotensin receptor blockers. Conclusion: The case report aims to present a case of Peripartum cardiomyopathy with early diagnosis and successful management in a secondary care level hospital. Peripartum (postpartum) cardiomyopathy is the most common cardiomyopathy in pregnancy, defined as an idiopathic cardiomyopathy that presents with heart failure secondary to left ventricular systolic dysfunction toward the end of pregnancy or after delivery, in the absence of any other cause of heart failure.  It is a diagnosis of exclusion, and the majority are diagnosed postpartum. Although the LV may not be dilated, the ejection fraction is nearly always reduced below 45%. Incidence of PPCM is 1:3000 to 1:15000 pregnancies. It is a major cause of morbidity and mortality if diagnosis gets delayed; therefore, early diagnosis and timely management can affect patients’ long-term prognosis. This case report aims to raise awareness in health professionals about the possibilities of PPCM and its symptoms, as in our case.
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An Update on Brachytherapy for Cervical Cancer: A Review

Published on: 31st October, 2025

Introduction: Cervical cancer remains one of the most common malignancies affecting women worldwide, with over 600,000 patients globally every year, and is a leading cause of cancer-related mortality in women. Although there have been advancements in both screening and prevention, radiation therapy, with or without chemotherapy, is the standard of care for treating locally advanced cervical cancer. Radiation typically consists of two methods, external beam radiation therapy (EBRT) and brachytherapy, which have both evolved in their own respective ways technologically and for patient accessibility. This article aims to review the different cervical cancer brachytherapy techniques, such as intracavitary and interstitial approaches, including their advantages and drawbacks.Methods: Resources on PubMed between the years 2000 and 2024 were reviewed based on their relevance to the approaches of brachytherapy. Articles were found through the use of key terms and Boolean operators such as ("cervical cancer,” AND “brachytherapy," OR “high dose rate brachytherapy,”) OR (“intracavitary,” OR “interstitial brachytherapy,” OR “hybrid brachytherapy,”). Discussion: Three techniques of brachytherapy are de: intracavitary brachytherapy (ICBT), interstitial brachytherapy (ISBT), and hybrid intracavitary/interstitial brachytherapy (HBT).Conclusion: Brachytherapy is a vital part of definitive cervical cancer treatment. While ICBT remains the standard of care for most cervical cancers, ISBT and HBT approaches remain important treatment options. HBT has been shown to address variances in patient anatomy and tumor geometry, resulting in better tumor dose coverage and improved outcomes through minimizing toxicity.
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Misoprostol Usage in the Kingdom of Bahrain: A Retrospective Study

Published on: 7th November, 2025

Introduction: The document introduces the topic of medical termination of pregnancy (MTP) using misoprostol, a synthetic prostaglandin E1 analogue. It discusses the advantages and challenges of this method, and the research gap in the Gulf region and the Middle East. It also states the aim of the study, which is to evaluate the safety, efficacy, and acceptability of misoprostol for MTP in Bahrain. Methods: The document describes the study design, data source, and inclusion criteria. It explains that the data was collected from the Hope system in King Hamad University Hospital and included women in the first and second trimester of pregnancy who were undergoing MTP as per the FIGO protocol. It also mentions the statistical analysis that was used to compare the outcomes of different regimens, dosages, and routes of administration of misoprostol. Results: The document reports the main findings of the study, such as the success and failure rates of MTP, the association between previous deliveries and MTP outcomes, the optimal number and route of misoprostol doses, the length of hospital stay, and the incidence of complications. It also presents some figures to illustrate the results. Discussion: The document interprets the results and compares them with previous studies. It highlights the high efficacy of the sublingual route of misoprostol but also acknowledges the side effects and limitations of this route. It suggests that two doses of 600mcg or 800mcg of misoprostol are sufficient for MTP. It also identifies the strengths and weaknesses of the study and proposes some future directions for research. Conclusion: The document concludes that the study provides a better understanding of the outcomes of misoprostol for MTP in a controlled environment. It asserts that misoprostol is a safe and effective option for women seeking abortion in the first and second trimester, especially in low-resource settings. It also emphasizes the need for evidence-based guidelines and counseling for misoprostol use.
Cite this ArticleCrossMarkPublonsHarvard Library HOLLISGrowKudosResearchGateBase SearchOAI PMHAcademic MicrosoftScilitSemantic ScholarUniversite de ParisUW LibrariesSJSU King LibrarySJSU King LibraryNUS LibraryMcGillDET KGL BIBLiOTEKJCU DiscoveryUniversidad De LimaWorldCatVU on WorldCat
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