Case Report

Predictors of positive treatment response to PTNS in women with overactive bladder

Suneetha Rachaneni*, Doyo Enki, Megan Welstand, Thomasin Heggie and Anupreet Dua

Published: 18 January, 2022 | Volume 5 - Issue 1 | Pages: 001-004

Percutaneous tibial nerve stimulation (PTNS) is a non-invasive treatment for overactive bladder (OAB). PTNS involves peripheral neuromodulation that uses electrical stimulation to target the spinal cord roots, mainly S3, which controls bladder function. Neuromodulation is postulated to be the effect of cross-signaling between sympathetic and parasympathetic post ganglionic nerve terminals and synapses, causing alteration of nerve signals involved in the voiding reflex. de Groat, et al. described this neurophysiological process and the neural circuits involved in controlling the lower urinary tract [1]. Stimulation of peripheral nerves and subsequent “cross-talk” at the level of the postganglionic neuroeffector junctions can modulate transmission and facilitate detrusor inhibition [2].

Read Full Article HTML DOI: 10.29328/journal.cjog.1001097 Cite this Article Read Full Article PDF


Posterior tibial nerve stimulation; Women; Predictors of success; Overactive bladder; Urinary incontinence


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