Abstract

Case Report

Hypertriglyceridemia induced acute pancreatitis in pregnancy: Learning experiences and challenges of a Case report

Sufia Athar*, Joohi Ramawat, Mohammad Abdel Aziz and Vincent Boama

Published: 14 May, 2019 | Volume 2 - Issue 1 | Pages: 006-012

Hyperglyceridemia induced pancreatitis in pregnancy accounts for 4% of all cases of acute pancreatitis. Though rare, hypertriglyceridemia induced pancreatitis may lead to fatal maternal and fetal complications, even maternal death. Its management during pregnancy remains a challenge for many physicians. Management options are limited in pregnancy. In the refractory cases, management options and timing of delivery is debatable. Here we report a case of hyperglyceridemia induced pancreatitis and the challenges faced in the management.

Read Full Article HTML DOI: 10.29328/journal.cjog.1001017 Cite this Article Read Full Article PDF

Keywords:

Hypertriglyceridemia, pancreatitis, pregnancy

References

  1. Ducarme G, Maire F, Chatel P, Luton D, Hammel P. Acute pancreatitis during pregnancy: a review. J Perinatol. 2014; 34: 87–94. Ref.: https://tinyurl.com/y6g4ah3h
  2. Igbinosa O, Poddar S, Pitchumoni C. Pregnancy associated pancreatitis revisited, Clinics and Research in Hepatology and Gastroenterology. 2013; 37: 177–181. Ref.: https://tinyurl.com/y2h9d2n7
  3. Zhang D, Huang Y, Yan L, PhuA, Ran X, et al. Thirty-eight cases of acute pancreatitis in pregnancy: a 6-year single center retrospective analysis. Journal of Huazhong University of Science and Technology. Medical Sciences. 2013; 33: 361–367. Ref.: https://tinyurl.com/y6hj9jw3
  4. Gupta N, Ahmed S, Shaffer L, Cavens P, Blankstein J. Severe Hypertriglyceridemia Induced Pancreatitis in Pregnancy. Case Rep Obstet Gynecol. 2014; 485493. 5. Ref.: https://tinyurl.com/y5bzqhp3
  5. Baumfeld Y, Novack L, Wiznitzer A, Sheiner E, Henkin Y, et al, Pre-Conception Dyslipidemia Is Associated with Development of Preeclampsia and Gestational Diabetes Mellitus. PLoS One. 2015; 10: e0139164. Ref.: https://tinyurl.com/y6kxl5lw
  6. Tang M, Xu JM, Song SS, Mei Q, Zhang LJ. What may cause fetus loss from acute pancreatitis in pregnancy: Analysis of 54 cases. Medicine (Baltimore) 2018; 97: 9755. Ref.: https://tinyurl.com/y6kf7k5w
  7. Tang SJ, Rodriguez-Frias E, Singh S, Mayo MJ, Jazrawi SF, et al. Acute pancreatitis during pregnancy. Clin Gastroenterol Hepatol. 2010; 8: 85-90. Ref.: https://tinyurl.com/y4p48vbm
  8. Berglund L, Brunzell JD, Goldberg AC, Goldberg IJ, Sacks F, et al. Endocrine society. Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2012; 97: 2969–2989. Ref.: https://tinyurl.com/y5ktta57
  9. Wang SH, Chou JC, Shangkuan WE, Wei KY, Pan JH, et al. Relationship between Plasma Triglyceride Level and Severity of Hypertriglyceridemic Pancreatitis. PLoS One. 2016; 11: e0163984. Ref.: https://tinyurl.com/y3y7w76h
  10. Desoye G, Schweditsch MO, Pfeiffer KP, Zechner R, Kostner GM. Correlation of hormones with lipid and lipoprotein levels during normal pregnancy and postpartum. J Clin Endocrinol Metab. 1987; 64: 704-712. Ref.: https://tinyurl.com/y49zcvn8
  11. Lippi G, Albiero A, Montagnana M, Salvagno GL, Scevarolli S, et al. Lipid and lipoprotein profile in physiological pregnancy. Clin Lab. 2007; 53: 173-117. Ref.: https://tinyurl.com/yxc7sgqg
  12. Alyse SG, Robert AH. Severe Hypertriglyceridemia in Pregnancy. J Clin Endocrinol Metab. 2012; 97: 2589–2596. Ref.: https://tinyurl.com/y63jdlml
  13. Basaran A. Pregnancy-induced hyperlipoproteinemia: review of the literature. Reprod Sci. 2009; 16: 431-437. Ref.: https://tinyurl.com/y4mx8msl
  14. Wong B, Ooi TC, Keely E. Severe gestational hypertriglyceridemia: A practical approach for clinicians. Obstet Med. 2015; 8: 158–167. Ref.: https://tinyurl.com/y3o2xtql
  15. Kastelein JJ, Maki KC, Susekov A, Ezhov M, Nordestgaard BG, et al. Omega-3 free fatty acids for the treatment of severe hypertriglyceridemia: the EpanoVa for Lowering Very high triglycerides (EVOLVE) trial. J Clin Lipidol. 2014; 8: 94–106. Ref.: https://tinyurl.com/y387fjto

Figures:

Figure 1

Figure 1

Figure 1

Figure 2

Figure 1

Figure 3

Figure 1

Figure 4

Similar Articles

Recently Viewed

Read More

Most Viewed

Read More

Help ?